Simoa Ultra-Sensitive Protein Profiling

The Quanterix Simoa ("single molecule array") technology represents the method of choice for all protein profiling applications that require ultrasensitive detection, due to low abundance of the proteins of interest and/or in case of precious limited samples.

The Simoa platform is based on the isolation of individual immunocomplexes via paramagnetic beads, but otherwise on standard ELISA reagents. By then measuring in femtoliter-sized wells yields a digital readout on the individual bead level, thus increasing the sensitivity of Simoa assays typically by a factor of 100 to 1,000 as compared to conventional assays. At the same time, even multiplexing of up to 10 analytes is feasible.

Please email us for more information about our Simoa services.